Avmacol Extra Strength
Avmacol Extra Strength
Nutramax Avmacol Extra Strength Sulforaphane Producing Supplement, 75 Tabs
Detoxification Support, #1 Researched Sulforaphane Producing Brand, with Glucoraphanin & Myrosinase, Published Studies
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Avmacol Extra Strength
Unlock Your Body’s Natural Defense
What is Avmacol Extra Strength
Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (containing beta-glucans) to support your body's natural detoxification process better than sulforaphane alone.Avmacol® Extra Strength provides glucoraphanin, also known as sulforaphane glucosinolate, and active myrosinase enzyme, which are the essential ingredients needed for sulforaphane production. Without active myrosinase enzyme, one may not be able to reap sulforaphane’s many health-promoting benefits.
Avmacol Extra Strength – Sulforaphane Production System
Supports Natural Detoxification, Cellular Health & Internal Defense
Detoxification Support
Avmacol® Extra Strength builds on the regular formula by adding beta-glucan to support your body’s natural detoxification process and overall cellular health, working better than sulforaphane alone.
Sulforaphane Generator
This formula features the Sulforaphane Production System®: broccoli seed and sprout extract (glucoraphanin) plus active myrosinase (Myrosimax®), helping your body make sulforaphane to support internal defense.
Works Synergistically
Avmacol® Extra Strength includes beta-glucan and maitake mushroom, known for their immune properties, to work synergistically with our sulforaphane-producing blend.
Backed by Research
Avmacol® has been selected for use in more sulforaphane human clinical trials than any other supplement. Our formula can be trusted by researchers and backed by science.
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Vegetarian
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Gluten-Free
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No Generic Equivalent
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Packaged in BPA-free bottles
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Numerous quality checks
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Validated with human research
Our exclusive Sulforaphane Production System® is validated in humans by measuring metabolites of sulforaphane collected in the urine.
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The choice for clinical studies
Because of the Sulforaphane Production System® exclusive to Avmacol®, numerous researchers have chosen this product for clinical studies worldwide.
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Directions for Use
Take 1 tablet per day or as directed by a physician. If you have any condition that requires medical attention always consult your physician before taking any dietary supplement.
Keep in a cool, dry place.
Important: Tamper evident seal under cap. Do not use if seal is broken or missing.
Directions for Use
Take 1 tablet per day or as directed by a physician. If you have any condition that requires medical attention always consult your physician before taking any dietary supplement.
Keep in a cool, dry place.
Important: Tamper evident seal under cap. Do not use if seal is broken or missing.
How Maitake Mushroom Extract Works in Combination with Sulforaphane
The Maitake mushroom extract (containing beta-glucans) works in combination with sulforaphane to support your body’s natural detoxification process better than sulforaphane alone. In addition, the Maitake mushroom extract found in Avmacol® Extra Strength provides the added bonus of immune support by promoting neutrophil function and natural killer cell activity.
The Science Behind Avmacol ® Extra Strength
The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.
Translocation of NRF2 into the Nucleus Following Exposure to Sulforaphane and Maitake Mushroom Extract
In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
NQO1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.
HO-1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.
Who Would Benefit from Avmacol ® Extra Strength?
We are capable of incredible things; and when our bodies get the support they need, the results can be amazing. Avmacol unleashes the power of broccoli to help your body fight off toxin-related stress at the cellular level.
The Avmacol® Difference
Avmacol® supports your body’s natural detoxification process. It features our Sulforaphane Production System®—combining glucoraphanin and active myrosinase enzyme to help your body produce sulforaphane. Selected for use in more sulforaphane human clinical trials than any other supplement, Avmacol® is trusted by researchers and families alike.
Backed by Research
- Avmacol® is the #1 researched sulforaphane producing brand.
- Avmacol® is thoroughly tested to meet the highest standards.
The Avmacol® Community
For families today, living healthy, balanced lives in harmony with our body’s natural processes is more complicated than ever. Our mission is to provide opportunities that make it easier to relieve stress on families all the way down to the cellular level.
FAQS
What is sulforaphane?
What is sulforaphane?
Sulforaphane is a phytochemical (a phytochemical is a biologically active compound of plant or vegetable origin) that helps increase the production of important Phase 2 detoxifying enzymes, promoting your body’s natural detoxification process, thereby supporting the elimination of potentially harmful metabolites. These harmful metabolites may cause damage to DNA, proteins and lipids in your cells. Sulforaphane is formed when a compound called glucoraphanin is transformed by an enzyme called myrosinase. Both glucoraphanin and active myrosinase enzyme are needed for sulforaphane production.
What is myrosinase and why is it so important?
What is myrosinase and why is it so important?
Myrosinase is an important enzyme required to convert glucoraphanin into sulforaphane. Additionally, it can be found in cruciferous vegetables, though it can become inactivated during the cooking process. It is important to remember that active myrosinase enzyme is necessary to convert glucoraphanin into sulforaphane.
What is glucoraphanin?
What is glucoraphanin?
Glucoraphanin is a compound that is present in many cruciferous vegetables, most notably in broccoli. It is an essential ingredient needed for sulforaphane production because it is sulforaphane’s direct precursor. The myrosinase enzyme processes glucoraphanin into sulforaphane.
Can I eat a lot of broccoli and get the benefits of sulforaphane?
Can I eat a lot of broccoli and get the benefits of sulforaphane?
Sulforaphane production is not predictable when eating broccoli. The levels of glucoraphanin and the active myrosinase enzyme vary greatly in vegetables you would typically buy at the market due to seed quality, soil composition, and other factors. Additionally, the myrosinase enzyme can be destroyed during the cooking process. Therefore, simply eating cruciferous vegetables, like broccoli, does not provide reliable amounts of glucoraphanin and the myrosinase enzyme and thus does not guarantee that your body will make sulforaphane.
What is the Sulforaphane Production System®?
What is the Sulforaphane Production System®?
The Sulforaphane Production System® is the foundation of the entire Avmacol® product line and includes the essential ingredients needed to promote sulforaphane production – glucoraphanin and active myrosinase enzyme.
Some supplements make me nauseous or leave a weird taste. These are fine. No issues at all.
Mostly plant-based diet. This fills in the gap for protective compounds. Concentrated and bioavailable.
Two pills with breakfast. Four months in. I feel more resilient especially during stressful work weeks.
Had a small order issue and they fixed it immediately and sent a free bottle as apology. Rare these days.
Sit at a computer all day. Wanted something to support my cells and detox. This fits the bill.
On my second bottle. Hard to say exactly what's happening but I feel good. Energy is steady, digestion is regular.
Used to get tension headaches all the time. Two months in and they're way less frequent.
Between work and kids I don't have time to be sick. Since I started taking this I've missed zero days.
Training for my 4th marathon. Recovery between long runs is better this cycle. Keeping it in the rotation.
Had a question about dosing and they emailed me back same day with a really detailed answer. Don't see that much anymore.
On my feet 10+ hours. Recovery matters. Also haven't caught every bug from the clinic. Win win.
Didn't expect brain benefits. But my afternoon fog is gone and I feel more focused. Nice surprise.
She's been on it forever and kept bugging me to try. Did, and now I'm a believer. No more 3pm coffee hits.
I have a sensitive gut and most supplements upset me. This one is totally fine.
Dealing with all the fun perimenopause symptoms. Added this and I feel more balanced. Not a cure but helps.
High-stress PR job. Since I started taking this, stress doesn't linger as long. Sleep is better too.
Perimenopause sucks. Started taking this and my hot flashes are less frequent. Can't say it's all from the pills but I'll take it.
Taste rich food all day long. Take this for liver support. Digestion is better and I don't feel sluggish after dinner service.
Have some chronic joint stuff. After a month on this, my morning stiffness is way better. Not a miracle but a noticeable difference.
Bought it for me, now he takes it too. We order together. He does construction and says recovery is better.
Stare at screens 10+ hours a day. Four months on this and eye strain feels less. Focus is better too.
My chiro suggested it. Easy to swallow, no stomach issues. Appreciate that the enzyme is active so I don't have to worry about gut conversion.
Three kids and a full-time job. I don't have time to get sick. This season I stayed healthy while everyone around me was down.
Appreciate that they don't make crazy claims. It supports your body's own detox pathways. Steady benefits over time.
My naturopath told me to try this for detox. Two months in and I genuinely feel lighter. Skin looks better too.
No weird fillers, no magnesium stearate, no artificial anything. Just good stuff. I'm picky and this passes.
Tried so many detox products that were just expensive urine. This one actually makes me feel different.
LPN. I tell family members to try this. Research is real, manufacturing is clean, price is fair.
Train for triathlons. Added this to my stack and recovery days feel shorter. Will keep buying.
Stack it with a glutathione precursor. Skin and energy are noticeably better. Synergistic.
Out in the sun all day. Added this and weekend recovery is better. Sleeping better too.
Bought it for detox but the best surprise was my skin. Breakouts calmed down after about 6 weeks. Didn't expect that.
High school teacher = germ central. Since starting this I've had zero sick days. Not taking any chances.